JJ Miranda, PhD

Assistant Professor of Biological Sciences

Department

Biology

Office

1305 Altschul Hall
Office Hours: By appointment (Zoom or in person)

Contact

For more details about our research, please visit the lab website.

Our team studies the gene regulation of human viruses that cause cancer. We have chosen to examine viruses not only because of relevance to human disease, but also because dramatic changes in transcription during the life cycle provide manipulatable switches for dissecting regulatory mechanisms. In addition to our efforts with discovery science, we are also working toward more translational goals by identifying small molecules that may serve as effective drugs in treating virus-associated malignancies.

  • Virology
  • Cancer
  • Gene Regulation

  • BIOL BC3320 Microbiology
  • BIOL BC3321 Laboratory in Microbiology
  • BIOL BC3591/2 Guided Research & Seminar
  • BIOL BC3593/4 Senior Thesis Research & Seminar
  • BIOL BC3597 Guided Research

  • Class of '21 Award, Reed College
  • Graduate Research Fellowship, National Science Foundation
  • Certificate of Distinction in Teaching, Harvard University

  • American Society for Microbiology

Recent papers highlight our work in understanding viral gene regulation during cancer.

Moquin SA, Thomas S, Whalen S, Warburton A, Fernandez SG, McBride AA, Pollard KS, Miranda JL. The Epstein-Barr virus episome maneuvers between nuclear chromatin compartments during reactivation. Journal of Virology. 2018;92(3):e01413-17.

He A, Miranda JL. JQ1 reduces Epstein–Barr virus-associated lymphoproliferative disease in mice without sustained oncogene repression. Leukemia & Lymphoma. 2018;59(5):1248-51.

Keck KM, Moquin SA, He A, Fernandez SG, Somberg JJ, Liu SM, Martinez DM, Miranda JL. Bromodomain and extraterminal inhibitors block the Epstein-Barr virus lytic cycle at two distinct steps. Journal of Biological Chemistry. 2017;292(32):13284-95.

In The News

“Barnard was one of the only schools where I was able to focus on biology and dance,” said the physical therapist.

April 26, 2022

The research technician delves into her work on antibiotics for Epstein-Barr virus regulation, her work in wastewater analysis, plus her passion for dance. #BarnardYearofScience

April 1, 2022

Today, we are sitting with Lina Ariyan (BC '22), a February Barnard graduate who joins the Miranda Lab for the spring semester alongside Nicole Rondeau (BC '18) under the mentorship of Professor JJ Miranda.

March 11, 2022