Biology Senior Theses

Biology majors must complete either a Senior Seminar in Biology (BIOL BC3590) or two semesters of Senior Thesis Research Seminar (BIOL BC3593 & BIOL BC3594y). Students who choose to complete two semesters of Senior Thesis Research work with a faculty advisor on an independent project to ultimately produce a primary research paper. Students then present their work at the end of their senior year in front of faculty, staff, and students.

Biology Senior Theses: Class of 2019

Research Symposium Program 

Presenters, titles, and mentors are listed below. 

Senior Thesis Research Presentations 

Senior Thesis Research Students (2019).

(From left to right.) Front: Jiani Liang, Kira Mitchel, Elizabeth (Betsy) Ladyzhets, and Binita Shah. Back: Natalie Kolba, Anita Pilar Montero, Joanly Sanchez, Hanna Scholze, Shannon MacLeod, Lillian Lawrence, Julia Pickel, and Nicki Mohamaddi.

9:45 am - Elizabeth (Betsy) Ladyzhets
Survey of deciduous tree and shrub biomass construction costs at Black Rock Forest demonstrates connection between ecological role and plant physiology
Kevin L. Griffin (Department of Ecology, Evolution, and Environmental Biology, Columbia University)

10:00 am - Binita Shah
Structures of intermediates in bacterial translation elongation using cryo-electron microscopy
Joachim Frank and Ziao Fu (Department of Biochemistry and Molecular Biophysics, Columbia University Irving Medical Center)

10:15 am - Anita Pilar Montero
The effects of maternal social integration and connectivity on offspring survival in a facultatively social mammal
Daniel T. Blumstein and Dana Williams (Department of Ecology and Evolutionary Biology, University of California, Los Angeles)

10:30 am - Joanly Sanchez
Transcriptional activation of metallothionein-3 (MT-3) through hypoxia: What is the role of the hypoxia response elements (HREs) in the metallothionein-3 (MT-3) promoter in hypoxia-mediated expression?
Mary Sever (Department of Chemistry, Barnard College)

10:45 am - Natalie Kolba
Regulation and function of the NO-cGMP pathway in Drosophila melanogaster sensory neurons
Wesley B. Grueber (Department of Physiology and Cellular Biophysics, Mortimer B. Zuckerman Mind Brain Behavior Institute)

11:00 am - Shannon Macleod
Characterizing the heat shock response in the alfalfa leafcutter bee
Jonathan W. Snow (Department of Biology, Barnard College)

11:15 am - Break

11:30 am - Kira Mitchel
Comparison of skeletal patterning following conditional deletion of Hoxa5 in somites and lateral plate mesoderm
Jennifer H. Mansfield (Department of Biology, Barnard College)

11:45 am - Hanna Scholze
Targeting the NAD salvage pathway in diffuse large B-Cell lymphoma
Riccardo Dalla-Favera and Claudio Scuoppo (Department of Pathology and Cell Biology, Institute for Cancer Genetics, Columbia University Irving Medical Center)

12:00 pm - Julia Pickel
Repeat culture as a predictor for fungal corneal ulcer treatment outcomes in the Mycotic Antimicrobial Localized Injection Trial
Jennifer Rose-Nussbaumer (Proctor Foundation for Research in Ophthalmology, University of California, San Francisco)

12:15 pm - Jiani Liang
Integrating neuralized 1b function in β cells
Utpal Pajvani (Department of Medicine: Division of Endocrinology, Columbia University Irving Medical Center)

12:30 pm - Lillian Lawrence
Investigating the role of Trans-Lesion Synthesis (TLS) of DNA in maintaining genome stability in the context of BRCA1 deficiency
Alberto Ciccia and Angelo Taglialatela (Department of Genetics and Development, Columbia University Irving Medical Center)

12:45 pm - Nicki Mohammadi
Understanding the effect of cell adhesion molecules on C. elegans behavior
Oliver Hobert and Emily Berghoff (Department of Biological Sciences, Columbia University)

Guided Research & Seminar Posters

Guided Research & Seminar Students (2019).

(From left to right.) Front: Sophia Liu, Tasneem Ebrahim, and Eva Schwartz. Back: Iasha Khan, Liza Casella, Anastasija Čupić, Dunay Bach, Nora McNamara-Bordewick, and Nina Tang. Not pictured: Jerica Tan and Zaza Vongkusolkit.

Poster 1 - Dunay Bach
Thermal stress induces tissue damage in the honey bee midgut
Jonathan Snow (Department of Biology, Barnard College)

Poster 2 - Liza Casella
Defining critical features of the immune microenvironment in neural tumors
Yvonne Saenger (Department of Medical Hematology and Oncology, Columbia University Irving Medical Center), Robyn Gartrell (Department of Pediatrics, Columbia University Irving Medical Center), and Andrew Silverman (Department of Pediatrics, New York Presbyterian Hospital)

Poster 3 - Anastaija Čupić
Towards understanding the role of LGP2 in the regulation of  the antiviral innate immune response
Adolfo García-Sastre and Lisa Miorin (Department of Microbiology, Global Health, and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai)

Poster 4 - Tasneem Ebrahim
How does glucose affect the epigenome?
Songtao Jia and Kehan Bao (Department of Biological Sciences, Columbia University)

Poster 5 - Iasha Khan
Understanding the role of the Cathepsin K expression downstream of the CD200-CD200R pathway in cutaneous squamous cell carcinoma metastasis
David Owens (Department of Dermatology, Pathology, and Cell Biology, Columbia University Irving Medical Center)

Poster 6 - Sophia Liu
Does a spoonful of sugar help the alcohol go down? Improving the palatability of ethanol increases consumption levels
John I. Glendinning (Department of Biology, Barnard College)

Poster 7 - Nora McNamara-Bordewick
Characterizing the effects of pharmacologic proteasome inhibition on the parasite N. ceranae and its honey bee host
Jonathan W. Snow (Department of Biology, Barnard College)

Poster 8 - Eva Schwartz
bc1 complex assembly in yeast mitochondria
Alexander Tzagoloff and Leticia V.R. Franco (Department of Biological Sciences, Columbia University)

Poster 9 - Jerica Tan
In vitro generation of human hypothalamic AGRP neurons
Claudia Doege (Department of Pathology and Cell Biology, Columbia University Irving Medical Center)

Poster 10 - Nina Tang
Mechanisms of cefepime resistance in cefepime-resistant piperacillin-tazobactam susceptible gram-negative bacterial clinical isolates
Anne-Catrin Uhlemann (Department of Medicine: Division of Infectious Diseases, Columbia University Irving Medical Center)

Poster 11 - Zaza Vongkusolkit
Quantification of neuroendocrine cells in wild-type mouse prostate
Michael M. Shen (Department of Medicine: Division of Hematology and Oncology, Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center) and Eva Y. Leung (Department of Nutrition and Metabolic Biology, Columbia University Irving Medical Center)

Senior Seminar in Data Intensive Approaches in Biology: Graphical Abstracts, Fall 2018

Iman Amir, Class of 2019
Jake Arlow, Class of 2019

Tatiana Becerra, Class of 2019

Nushrat Chowdhury, Class of 2019

Alyson Dennis, Class of 2019

Caroline Dolt, Class of 2019

Jenny Goodgal, Class of 2019

Olivia Korostoff-Larsson, Class of 2019

Betsy Ladyzhets, Class of 2019

Taylor Leong, Class of 2019

Catherine Miller, Class of 2019

Ariel Tzamarot, Class of 2019

Emma Vincent, Class of 2019


Biology Senior Theses: Class of 2018

Student Thesis Title
Amelia Baier Role of FGFR Signaling in Cutaneous Merkel Cell Carcinoma Pathogenesis
Jenna Bergmann Effects of Tissue-Specific Deletion of Hoxa5 by Prx1-Cre on Perinatal Survival and Axial Skeletal Patterning
Mary Chalkley Determining the Role of Nkx2.2 in Cell Fate Determination
Sarah Chaudhry Group A Streptococcous Infections in Mice Induce Th17 Cells into the Olfactory Bulb
Gabi Gelnavis FoxO 1,3,4 Transcription Factors Regulate Scavenger Receptor Class B Member 1 Protein and Hepatic Lipase in the Reverse Cholesterol Transport Pathway
Tasnin Kabir Constructing a Functional Heterologous Cell Line to Molecularly Characterize the IRE-1 Pathway in Apis mellifera
Esther Kang The Impacts of Hurricane Matthew on the Coastal Phytoplankton Community of the mid-Atlantic Bight
Lena Kogan Development and Differentiation of the Somatic Progenitor Cells in the Drosophila Ovary
Hana Koob Aim17p-Localization of Mob1p in Budding Yeast with Mitochondrial Inheritance Defects
Olivia Korostoff-Larson Mutational Analysis of NUCB1 Mediated Inhibition of Amyloid Aggregation
Sabrina Krebs Refining Murine Blast Injury Models of Severe TBI for Future Studies of Disorders of Arousal
Madison Lichak Betta Fish:  Developing a New Model for Studying Behavior and Pigmentation
Meaghan Marohn Targeted Mutagenesis of Manduca sexta Gustatory Receptor Genes using CRISPR/Cas9
Elizabeth McAneny Motor-Cognitive Dual-Task Performance and Falls in People with Huntington's Disease
Samantha Ong Dissecting Ventral Hippocampus Contextual memory Circuit Activity
Lia Parkin Synonymous Codon Bias
Nicole Rondeau Upregulation of Lactate Dehydrogenase and Glycine N-Methyltransferase in Situations of Cellular Stress in Apis mellifera
Emma Ruskin MicroUnity:  Harnessing the Power of Laboratory Research in STEAM Education
Kathyana Santiago Improving Hybridoma Fusion Efficiency
Emma Vincent Transmission of Respiratory Viruses Among Families in Upper Manhattan
Amen Wiqas Mast Cells and Zinc Homeostasis in the Brain